Wei Qin, Dongli Zhang, Liyan Zhang*
Department of Integrated Traditional Chinese and Western Medicine, Affiliated Hospital of Hebei University, Baoding 071000, Hebei, China
- Corresponding Author: zhangliyan_edu@outlook.com; Email: tt120626@163.com
Abstract
Objective
We investigated the clinical impact of traditional Chinese medicine in combination with chemotherapy in treating extensive-stage small cell lung cancer. Methods: One hundred and two patients admitted to our hospital from October 2022 to August 2023 were included. The control group received irinotecan hydrochloride for injection. On the basis of the control group, the study group was given Kangai injection.
Results
The objective response rate and clinical benefit rate values of the study group presented higher than the control group, the decline of tumor markers was more obvious, the levels of CD4+ and CD4+/CD8+ were higher, the CD8+ level was lower. Incidence of adverse drug reactions in the study group (7.84%) presented reduction as relative to the control group (25.49%). After therapy, the elevation of quality of life score was more obvious in the study group as relative to the control group.
Conclusion
Traditional Chinese medicine in combination with chemotherapy can promote the short-term efficacy, reduce the levels of tumor markers, regulate the immune function of patients, lessen the occurrence of adverse reactions, along with help promote the quality of life of patients with extensive-stage small cell lung cancer.
Keywords: Small cell lung cancer, Chemotherapy, Traditional Chinese medicine, Kangai injection, Immune function