Clinical study on the treatment of psoriasis (liver depression and blood heat type) with Tianqi Qingyin decoction

Bin Zhou¹, Yin Xue^2,*

1. Department of Dermatological, Changzhou Wujin People’s Hospital, Tianning District, Changzhou, Jiangsu, 213100, China.
2. Department of TCM, Changzhou Wujin People’s Hospital, Tianning District, Changzhou, Jiangsu, 213100, China.

• Corresponding Author:Yin Xue; E-mail: xueyin861101@163.com

Abstract
Objective
To probe the effect of Tianqi Qingyin decoction on psoriasis (liver depression and blood heat type).
Methods
From January 2021 to April 2022, 80 patients treated in our hospital were collected and randomly separated into study group (SG) and control group (CG), each group had 40 cases. The CG was given compound Qingdai Capsule. The SG was given Tianqi Qingyin decoction. The clinical effect, PASI scores, cytokine IL-17 and TNF-α contents, DLQI scores and occurrence of adverse reactions in both groups were compared.
Results
The total effective rate in the SG was elevated relative to the CG (χ2=6.28, P<0.05). No difference was seen in PASI scores, cytokine IL-17 and TNF-α contents and DLQI scores between both groups previous to treatment (P>0.05). After treatment, all above indexes were declined in both groups, and those of the SG were lessened relative to the CG (P<0.05). The occurrence of adverse reactions in the SG was reduced in comparison with the CG (P<0.05).
Conclusion
Tianqi Qingyin decoction can promote clinical efficacy in treating liver depression and blood heat type psoriasis and is worthy of further clinical application.
Keywords: Tianqi Qingyin decoction, psoriasis, liver depression and blood heat type, IL-17, TNF-α.