A rare disease with pregnancy: Castleman case report

Özen Esra Karaman1*, Çetin Kılıççı, Pelin Özdemir Önder

  1. Fenerbahçe University, Faculty of Health Sciences, Department of Midwifery, Istanbul/Turkey
  2. Zeynep Kamil Woman and Child Diseases Education and Research Hospital, Gynecology and Obstetrics Clinic, Istanbul/Turkey

*Corresponding Author: Özen Esra Karaman

Castleman’s disease was first described by Castleman et al. in 1956 as a non-lymphoproliferative disease.1 Castleman’s disease (CD), or angiofollicular lymphoid hyperplasia, is a rare disease with unknown etiology that can be easily misdiagnosed as lymphoma, neoplasm, or infection. Very few cases of pelvic origin and observed in pregnancy have been reported in the literature and are usually asymptomatic. Preoperative diagnosis is very difficult due to nonspecific imaging findings and rarity; most cases are diagnosed based on postoperative pathological examination. In this paper, a case of a 36-year-old pregnant woman suspected of adnexal origin in the uterine posterolateral, which was detected incidentally by ultrasound, was presented. The patient underwent a successful mass excision. Pathology of mass observed to be in the pelvic retroperitoneum was detected as localized unicentric and hyaline vascular CD. The study was conducted to discuss the diagnostic tools and perioperative management needed to identify the retroperitoneal unicentric Castleman case.
Keywords: Adnexal mass, pelvic tumor, pelvic pain, Castleman’s disease, lymph node, pregnancy, hyaline, vascular

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